Luís Filipe de Sepúlveda Silva Santos

Invited Teaching Assistant

Generic Bio

Luís Silva Santos, PharmD. Born in Coimbra (1978). Degree in Pharmaceutical Sciences from Universidade de Coimbra (Faculty of Pharmacy) and Master in Experimental Pathology from the same University (Faculty of Medicine). Postgraduate studies in Genetic Toxicology and Toxicogenomics (Universidade Nova de Lisboa) and in Bioethics (Universidade Católica Portuguesa). Currently awaiting the appointment of public presentation of his PhD thesis in order to obtain the Doctorate Degree in Biomedical Sciences by Universidade do Porto (Instituto de Ciências Biomédicas Abel Salazar). Teaches at Universidade Católica Portuguesa since 2006, where he is currently responsible for the Pharmacology, Toxicology and Immunology disciplinary areas of both the Integrated Master Course in Dentistry and the Biomedical Sciences Degree. Member of the Pedagogical Council of the Faculty of Dentistry of Universidade Católica Portuguesa. Invited researcher at the Centre for Toxicogenomics and Human Health (ToxOmics), NOVA Medical School (Universidade Nova de Lisboa), where he develops research work in the field of Medicine and Biomedicine, sub-areas Pharmacology, Toxicology and Molecular Diagnosis. He has 9 scientific articles published in indexed peer-reviewed journals, prepared in collaboration with 32 other co-authors and cited by 214 indexed articles (h-index = 5; Scopus data). 6 oral communications and 22 panel communications (“poster”) at scientific events.

Other

#079 Biomarcadores de genotoxicidade em imagiologia medico-dentária: uma revisão sistemática

Luís Filipe de Sepúlveda Silva Santos 2023. Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial
Paper

#146. miRNAs salivares como biomarcadores da Diabetes Mellitus tipo II

Maria José Serol de Brito Correia, Nuno Ricardo das Neves Rosa, Marlene Maria Tourais de Barros & Luís Filipe de Sepúlveda Silva Santos (with Alexandra Martins). 2016. Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial
Other

Avaliação da saúde oral numa população rural

Luís Filipe de Sepúlveda Silva Santos & Nélio Jorge Veiga (with Carla Barata). 2008. III Jornadas de Medicina Dentária da Universidade Católica Portuguesa
Other

Biomarcadores de genotoxicidade em imagiologia medico-dentária

Luís Filipe de Sepúlveda Silva Santos (with Susana Alonso). 2023. XLIII Congresso Anual da Sociedade Portuguesa de Estomatologia e Medicina Dentária, Oeira, Portugal, 12/10/23
Other

Cytogenetic changes in exfoliated oral mucosa cells as effect biomarkers in dental diagnostic imaging

Luís Filipe de Sepúlveda Silva Santos (with Susana Alonso). 2023. National Meeting of the Center for Interdisciplinary Research in Health (CIIS), Sintra, Portugal, 31/03/23
Other

DNA damage in pathology staff occupationally exposed to formaldehyde

Luís Filipe de Sepúlveda Silva Santos (with João Paulo Teixeira). 2008. 99th Annual Meeting of the American Association for Cancer Research
Other

DNA repair polymorphisms and oral cancer risk

Luís Filipe de Sepúlveda Silva Santos (with AM Marques). 2014. 7th Santorini Conference, Biologie Prospective , Santorini Island, Greece, 25/09/14
Other

DNA repair SNPs as biomarkers of therapeutic response in oral cancer patients

Luís Filipe de Sepúlveda Silva Santos (with Bruna Mirahy). 2023. National Meeting of the Center for Interdisciplinary Research in Health (CIIS), Sintra, Portugal, 31/03/23
Other

DNA repair SNPs as genetic modulators of individual susceptibility to differentiated thyroid cancer and response to radioiodine therapy

Luís Filipe de Sepúlveda Silva Santos (with Santos, Luis S.). 2021.
Other

DNA repair SNPs as modulators of response to cancer radiotherapy

Luís Filipe de Sepúlveda Silva Santos (with A. M. Marques). 2015. Drug Metabolism and Personalized Therapy
Other

Estudo biomorfológico do intestino grosso na administração experimental de cerveja

Luís Filipe de Sepúlveda Silva Santos (with Santos, Luis S.). 2006.
Other

Evaluation of formaldehyde exposure in the work environment

Luís Filipe de Sepúlveda Silva Santos (with S. Costa). 2014. 7th Santorini Conference, Biologie Prospective , Santorini Island, Greece, 25/09/14
Other

Excision repair SNPs may influence the extent of DNA damage from radioiodine therapy in lymphocytes from thyroid cancer patients

Luís Filipe de Sepúlveda Silva Santos (with Santos, Luis S.). 2023. National Meeting of the Center for Interdisciplinary Research in Health (CIIS), Sintra, Portugal, 31/03/23
Other

Farmacología de la inmunidad

Luís Filipe de Sepúlveda Silva Santos (with Silva Santos, Luís). 2011.
Book

Farmacología del crecimiento neoplásico

Luís Filipe de Sepúlveda Silva Santos (with Luís Filipe de Sepúlveda Silva Santos). 2011.
Paper

Genetic effects and biotoxicity monitoring of occupational styrene exposure

Luís Filipe de Sepúlveda Silva Santos (with Rueff, J.). 2009. Clinica Chimica Acta
Paper

Genotoxic damage in pathology anatomy laboratory workers exposed to formaldehyde

Luís Filipe de Sepúlveda Silva Santos (with Costa, S.). 2008. Toxicology
Other

Human Genome Project: a window of opportunity

Luís Filipe de Sepúlveda Silva Santos (with Luís Filipe de Sepúlveda Silva Santos). 2002. 48th IPSF World Congress
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Identification of miRNAs with potential utility as salivary biomarkers for type II diabetes

Nuno Ricardo das Neves Rosa & Luís Filipe de Sepúlveda Silva Santos (with A. Martins). 2016. Clinical Chemistry and Laboratory Medicine
Other

In silico analysis of non-synonymous SNPs in toxicogenomic studies

Luís Filipe de Sepúlveda Silva Santos (with Santos, Luis S.). 2013. Second International Conference on Occupational and Environmental Toxicology, Porto, Portugal, 16/09/13
Other

In silico analysis of non-synonymous SNPs in toxicogenomic studies: impact of genetic variation on the FANC DNA repair pathway and susceptibility to DPC- and ICL-inducing chemical agents

Luís Filipe de Sepúlveda Silva Santos (with Luís Filipe de Sepúlveda Silva Santos). 2013. International Conference on Occupational & Environmental Toxicology (ICOETox 2013)
Other

In silico analysis of SNPs in pharmacogenomic studies: predictive functional analysis of SLC5A5 gene variants and potential impact on radioactive iodine (131-I) therapy response

Luís Filipe de Sepúlveda Silva Santos (with Silva Santos, Luís). 2013. Second ESPT Conference “Pharmacogenomics: From Cell to Clinic”
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In silico analysis of SNPs in pharmacogenomic studies: predictive functional analysis of SLC5A5 gene variants and potential impact on radioactive iodine (131-I) therapy response

Luís Filipe de Sepúlveda Silva Santos (with Luís Filipe de Sepúlveda Silva Santos). 2013. Second ESPT Conference ¿Pharmacogenomics: From Cell to Clinic¿
Paper

Increased levels of chromosomal aberrations and DNA damage in a group of workers exposed to formaldehyde

Luís Filipe de Sepúlveda Silva Santos (with Costa, S.). 2015. Mutagenesis
Paper

Micronuclei Formation upon Radioiodine Therapy for Well-Differentiated Thyroid Cancer: The Influence of DNA Repair Genes Variants

Luís Filipe de Sepúlveda Silva Santos (with Luís S. Santos). 2020. Genes
Other

miRNAs as potential salivary biomarkers in periodontitis

Nuno Ricardo das Neves Rosa & Luís Filipe de Sepúlveda Silva Santos (with Santos, Luis S.). 2016. Clinical Chemistry and Laboratory Medicine
Other

miRNAs como biomarcadores

Nuno Ricardo das Neves Rosa & Luís Filipe de Sepúlveda Silva Santos (with S Rei). 2015. I Jornadas Científicas da Primavera, Viseu, Portugal, 20/03/15
Other

MiRNAs salivares como biomarcadores da diabetes Mellitus tipo II (DMTH)

Paper

Mismatch repair single nucleotide polymorphisms and thyroid cancer susceptibility

Luís Filipe de Sepúlveda Silva Santos (with Santos, L.S.). 2018. Oncology Letters
Other

Mismatch repair SNPs and thyroid cancer susceptibility

Luís Filipe de Sepúlveda Silva Santos (with Santos, Luis S.). 2015. Drug Metabolism and Personalized Therapy
Paper

Newly identified synergy between clopidogrel and calcium-channel blockers for blood pressure regulation possibly involves CYP2C19 rs4244285

Luís Filipe de Sepúlveda Silva Santos (with Stathopoulou, M.G.). 2013. International Journal of Cardiology
Book Chapter

Optimización de la adecuación terapéutica en pacientes polimedicados

Luís Filipe de Sepúlveda Silva Santos (with Luís Filipe de Sepúlveda Silva Santos). 2011. Polimedicación y Salud: Estrategias para la adecuación terapéutica
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Personalized cancer radiotherapy

Luís Filipe de Sepúlveda Silva Santos (with AM Marques). 2016. Clinical Chemistry and Laboratory Medicine
Paper

Polymorphisms in base excision repair genes and thyroid cancer risk

Luís Filipe de Sepúlveda Silva Santos (with Santos, L.S.). 2012. Oncology Reports
Other

Polymorphisms in DNA repair genes and non-familiar thyroid cancer risk

Luís Filipe de Sepúlveda Silva Santos (with Bruno Gomes). 2010. AACR Special Conference in Cancer Research - The Future of Molecular Epidemiology: New Tools, Biomarkers, and Opportunities
Other

Polymorphisms in DNA repair genes and non-familiar thyroid cancer risk

Luís Filipe de Sepúlveda Silva Santos (with BC Gomes). 2010. AACR Special Conference in Cancer Research , Miami, United States, 6/06/10
Other

Pontos no CIIS | SalivaTec

Luís Filipe de Sepúlveda Silva Santos (with Ana Sofia Duarte). 2022.
Other

Synergy between clopidogrel and calcium-channel blockers for blood pressure regulation possibly involves CYP2C19 polymorphism

Luís Filipe de Sepúlveda Silva Santos (with Maria G. Stathopoulou). 2013. Drug Metabolism and Personalized Therapy
Other

The potential contribution of DNA repair SNPs to thyroid cancer susceptibility

Luís Filipe de Sepúlveda Silva Santos (with Santos, Luis S.). 2016. 2º Simpósio de Ciências e Tecnologias da Vida e da Saúde, Porto, Portugal, 30/09/16
Other

The potential contribution of SNP-SNP interactions within the DNA mismatch repair pathway to thyroid cancer susceptibility

Luís Filipe de Sepúlveda Silva Santos (with Santos, Luis S.). 2017. Fourth ESPT Conference , Catania, Italy, 4/10/17
Other

The potential impact of DNA repair SNPs on DNA damage levels of lymphocytes from 131I-treated thyroid cancer patients

Luís Filipe de Sepúlveda Silva Santos (with Santos, Luis S.). 2017. Fourth ESPT Conference , Catania, Italy, 4/10/17
Paper

The role of CCNH Val270Ala (rs2230641) and other nucleotide excision repair polymorphisms in individual susceptibility to well-differentiated thyroid cancer

Luís Filipe de Sepúlveda Silva Santos (with Santos, L.S.). 2013. Oncology Reports
Other

The role of CCNH Val270Ala and other nucleotide excision repair polymorphisms on individual susceptibility towards thyroid cancer

Luís Filipe de Sepúlveda Silva Santos (with Silva Santos, Luís). 2012. 6th Santorini Conference Biologie Prospective "Systems Biology and Personalized Health Science and Translation"
Paper

Thyroid Cancer: The Quest for Genetic Susceptibility Involving DNA Repair Genes

Other

Thyroid Cancer: The Quest for Genetic Susceptibility Involving DNA Repair Genes

Luís Filipe de Sepúlveda Silva Santos (with Santos, Luis S.). 2019. 2º Encontro de Ciência da NOVA, Lisboa, Portugal, 18/09/19