Ana Sofia Direito dos Santos Duarte

Assistant Professor

PhD in Biochemistry (2006) by the University of Aveiro, she is currently an assistant professor at the Universidade Católica Portuguesa, at the Faculty of Dental Medicine - Viseu. Her experience as a teacher includes teaching disciplines in several courses and mentoring several PhD and Master students.
Current research interests focus on the molecular mechanisms involved in the cytotoxicity and virulence of microorganisms and their associated biotechnological potential. She has also developed studies for the characterization of biomaterials (polymers and nanoparticles) in several applications, namely with regard to the biocompatibility of materials and their antimicrobial properties, for biomedical application. She has complementary training in valuing intellectual property and disseminating science. She has participated in different initiatives that aim to communicate science in various aspects, from the transfer of technology to the social and academic valorization of science.

Paper

<em>Lasiodiplodia theobromae</em> as a Producer of Biotechnologically Relevant Enzymes

Ana Sofia Direito dos Santos Duarte 2018. International Journal of Molecular Sciences
Paper

A multi-omics analysis of the grapevine pathogen Lasiodiplodia theobromae reveals that temperature affects the expression of virulence- and pathogenicity-related genes

Ana Sofia Direito dos Santos Duarte 2019. Scientific Reports
Paper

Aeromonas molluscorum Av27 is a potential tributyltin (TBT) bioremediator: Phenotypic and genotypic characterization indicates its safe application

Ana Sofia Direito dos Santos Duarte (with Cruz, A.). 2013. Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology
Paper

Aeromonas piscicola AH-3 expresses an extracellular collagenase with cytotoxic properties

Ana Sofia Direito dos Santos Duarte 2014. Letters in Applied Microbiology
Paper

Bacterial collagenases - A review

Ana Sofia Direito dos Santos Duarte 2014. Crit Rev Microbiol
Paper

Bacterial collagenases - A review

Ana Sofia Direito dos Santos Duarte (with Duarte, A. S.). 2016. Critical Reviews in Microbiology
Paper

Bioactivity and antibacterial activity against E-coli of calcium-phosphate-based glasses: Effect of silver content and crystallinity

Ana Sofia Direito dos Santos Duarte (with Capela, M. N.). 2017. Ceramics International
Paper

Cardosins applied in neuronal embryonic cell culture

Nuno Ricardo das Neves Rosa & Ana Sofia Direito dos Santos Duarte (with Ana Sofia Duarte). 2005. European Journal of Neurology
Paper

Cardosins improve neuronal regeneration after cell disruption: A comparative expression study

Ana Sofia Direito dos Santos Duarte & Marlene Maria Tourais de Barros (with Duarte, A.S.). 2009. Cell Biology and Toxicology
Paper

Cardosins: A new and efficient plant enzymatic tool to dissociate neuronal cells for the establishment of cell cultures

Ana Sofia Direito dos Santos Duarte, Nuno Ricardo das Neves Rosa & Marlene Maria Tourais de Barros (with Duarte, A.S.). 2007. Biotechnology and Bioengineering
Other

Characterization of multi-drug resistant Escherichia coli in the UV-treated outflow of an urban wastewater treatment plant

Ana Sofia Direito dos Santos Duarte (with Tavares, Rafael D. S.). 2019.
Paper

Chitosan and polyethylene glycol based membranes with antibacterial properties for tissue regeneration

Ana Sofia Direito dos Santos Duarte (with Pereira, I.C.). 2019. Materials Science and Engineering C
Paper

Chitosan and polyethylene glycol based membranes with antibacterial properties for tissue regeneration.

Ana Sofia Direito dos Santos Duarte 2018. Materials science & engineering. C, Materials for biological applications
Other

Cloning and expression of necrosis and ethylene-inducing proteins (NLPs) from Neofusicoccum parvum.

Ana Sofia Direito dos Santos Duarte (with Duarte, Ana). 2017. 10th International Workshop on Grapevine Trunk Diseases. 4-7 July 2017, REIMS, France.
Other

Collagenases for biotechnological applications (C.P.31).

Ana Sofia Direito dos Santos Duarte (with Duarte, Ana). 2015. IV Encontro Nacional de Pós-Graduação em Ciências Biológicas, 30 de Março-2 de Abril 2015, Universidade de Aveiro.
Paper

Comparasion of hydrolytic activity of cardosin A and B on Collagen i

Ana Sofia Direito dos Santos Duarte & Marlene Maria Tourais de Barros (with Cabrita, A.M.S.). 1997. FASEB Journal
Book Chapter

Discurso escrito: Como preparar um texto científico

Ana Sofia Direito dos Santos Duarte (with Duarte, Ana). 2019. Comunicação de Ciência - das universidades ao grande público
Paper

Effect of temperature on the phytotoxicity and cytotoxicity of Botryosphaeriaceae fungi

Paper

Effect of thermal stress on the proteome of Aeromonas

Ana Sofia Direito dos Santos Duarte (with Honorio, F.). 2013. Current Opinion in Biotechnology
Paper

Effect of γ-Aminobutyric Acid (GABA) on the Metabolome of Two Strains of Lasiodiplodia theobromae Isolated from Grapevine

Ana Sofia Direito dos Santos Duarte (with Maria Michela Salvatore). 2020. Molecules
Paper

Evaluation of cardosin A as a probe for limited proteolysis in non-aqueous environments - Complex substrates hydrolysis

Ana Sofia Direito dos Santos Duarte & Marlene Maria Tourais de Barros (with Sarmento, A.C.). 2006. Enzyme and Microbial Technology
Paper

Genotypic and phenotypic traits of blaCTX-M-carrying Escherichia coli strains from an UV-C-treated wastewater effluent

Ana Sofia Direito dos Santos Duarte (with Tavares, Rafael D.S.). 2020. Water Research
Paper

Immobilisation of cardosin A in chitosan sponges as a novel implant for drug delivery

Ana Sofia Direito dos Santos Duarte & Marlene Maria Tourais de Barros (with Pereira, A.O.). 2005. Current Drug Discovery Technologies
Book Chapter

Linear polymers to inhibit bacterial Quorum Sensing

Ana Sofia Direito dos Santos Duarte (with Duarte, Ana). 2016. Polymer science: research advances, practical applications and educational aspects
Other

Método para produção de colagenase recombinante para digestão de colagénios

Ana Sofia Direito dos Santos Duarte (with António Carlos Matias Correia). 2015.
Other

Método para produção de colagenase recombinante para digestão de colagénios

Ana Sofia Direito dos Santos Duarte (with Duarte, Ana). 2018.
Paper

Novel linear polymers able to inhibit bacterial quorum sensing

Ana Sofia Direito dos Santos Duarte 2015. Macromolecular Bioscience
Other

Production of a novel collagenase and applications. European Biotechnology

Ana Sofia Direito dos Santos Duarte (with Duarte, Ana). 2014. European Biotechnology Congress 2014, 15-18 May, Lecce, Italy.
Paper

Production of toxic metabolites by two strains of Lasiodiplodia theobromae, isolated from a coconut tree and a human patient

Ana Sofia Direito dos Santos Duarte (with Carina Félix). 2018. Mycologia
Paper

Secondary metabolites produced by grapevine strains of Lasiodiplodia theobromae grown at two different temperatures

Ana Sofia Direito dos Santos Duarte (with Carina Félix). 2019. Mycologia
Paper

Secondary Metabolites Produced by Macrophomina phaseolina Isolated from Eucalyptus globulus

Ana Sofia Direito dos Santos Duarte (with Maria Michela Salvatore). 2020. Agriculture
Paper

Synthetic polymers capable of suppressing virulence of bacterial fish pathogens

Ana Sofia Direito dos Santos Duarte (with Cavaleiro, E.). 2011. Current Opinion in Biotechnology
Paper

Temperature modulates the secretome of the phytopathogenic fungus Lasiodiplodia theobromae

Ana Sofia Direito dos Santos Duarte (with Félix, C.). 2016. Frontiers in Plant Science
Paper

The characterisation of the collagenolytic activity of cardosin A demonstrates its potential application for extracellular matrix degradative processes

Ana Sofia Direito dos Santos Duarte & Marlene Maria Tourais de Barros (with Duarte, A.S.). 2005. Current Drug Discovery Technologies
Paper

Toxicity of Recombinant Necrosis and Ethylene-Inducing Proteins (NLPs) from Neofusicoccum parvum

Ana Sofia Direito dos Santos Duarte (with Forough Nazar Pour). 2020. Toxins
Book

Tracking the functional meaning of the human oral-microbiome protein-protein interactions

Paper

Unveiling Biological Activities of Marine Fungi: The Effect of Sea Salt

Ana Sofia Direito dos Santos Duarte 2021. Applied Sciences