The Immunology Curricular Unit has the general objective of providing the student with the necessary knowledge to understand the cellular and molecular mechanisms involved in the immunological response (IR) that lead to the disease, whether due to a deficit in response (e.g. immunodeficiencies) or exaggeration of the response. with tissue or organ damage (e.g. hypersensitivities), or due to an aberrant response (immunoproliferative syndromes), and the student must ultimately understand the cellular and molecular mechanisms associated with immune system dysfunction (autoimmune diseases, primary and acquired immunodeficiencies, immunoproliferative syndromes , neoplasms, transplants). The Curricular Unit is also dedicated to presenting the applications of Immunology to laboratory diagnosis (in a clinical context and scientific research) and to pharmacology and therapeutics. The specificity of the antigen-antibody bond makes it possible to create original diagnostic systems and develop innovative therapeutic approaches that have contributed to accelerated progress in the area of biomedical sciences with extremely relevant applications in everyday clinical practice. Some of these potential applications will be presented (both at the level of immunodiagnosis and at the level of immunopharmacology) and the different pharmacological strategies available to regulate the activity of the Immune System (immunomodulatory drugs). The transposition of previously learned knowledge about immunological mechanisms to the specific context of the oral cavity will also be explored in other classes. Finally, the aim is to raise student awareness of the importance of developing and promoting scientific research in Immunology, specifically in the context of Biomedical Sciences.
Immunology
4 ECTS / Semestral / Portuguese